Current Issue : January - March Volume : 2020 Issue Number : 1 Articles : 5 Articles
Background: Sickle cell disease (SCD) is associated with an increased risk of\nmedical complications during pregnancy and they constitute a very high-risk\ngroup with associated increased maternal and perinatal morbidity and mortality\nespecially in a low resource setting. Objective: To determine the pregnancy\noutcomes among women with sickle cell disease delivered at Alex Ekwueme\nFederal University Teaching Hospital, Abakaliki. Materials and methods:\nThis was a 7-year retrospective case-control study undertaken from\nJanuary 2012 to December 2018 that compared pregnancy outcomes among\nwomen with and without haemoglobinopathy in pregnancy managed at Alex\nEkwueme Federal University Teaching Hospital, Abakaliki (AEFUTHA). The\nstatistical analysis was done using SPSS version 22. Results: The incidence of\nSCD in pregnancy was 6.9 per 1000 deliveries. The age distribution of the\nwomen ranged from 18 to 45 years of age with a mean of.........................
Background: Preterm delivery is a major cause of perinatal morbidity and\nmortality globally. In more than half of the cases, the exact cause is unknown\nand it is largely unpredictable. Certain maternal, social and demographic\ncharacteristics are risk factors and often help to predict and prognosticate the\nneonatal outcomes. Objective: This study was designed to determine the maternal\nsocio-demographic characteristics and neonatal outcomes of patients\nmanaged for singleton preterm delivery in Alex Ekwueme Federal University\nTeaching Hospital, Abakaliki. Method: This was a 4-year retrospective analysis\nof patients managed for preterm birth from 1st January 2012 through 31st\nDecember 2015. Results: Over the study period there were a total number of\n623 singleton preterm deliveries in the facility, while there were 9647 deliveries\nin the facility; the preterm birth rate was 6.5% or 65 per 1000 deliveries������...
Introduction: Takayasuâ??s arteritis (TA) is a rare systemic, chronic inflammatory,\nprogressive, idiopathic disease of aorta and its main branches. Takayasuâ??s\narteritis causes narrowing, occlusion and aneurysm of arteries. The\netiology of TA is still unknown. It may be autoimmune or genetic in origin or\ninfective diseases. It is commonly found in Asia and oriental countries.\nWorldwide annual incidence is 1.2 - 2.6 cases/million. Women are affected in\n80% - 90% of cases with age of onset below 40 years. TA does not worsen or\nimprove with pregnancy but has adverse effect on pregnancy in the form of\nabortion, Intrauterine fetal death, superimposed preeclampsia, Intrauterine\ngrowth restriction, abruption and congestive heart failure. Because the disease\nis common in women of childbearing age, management of pregnancy in these\npatients becomes important; however optimal management for pregnant patients\nwith this disease has not yet been established. Due to the manifold cardiovascular\ncomplications that can occur in the course of the disease, management\nof pregnancies in TA patients is a challenge for the clinician. An interdisciplinary\ncollaboration of obstetrician, rheumatologist, cardiologist and\nanaesthetist is necessary to improve maternal and fetal prognosis. This was\nthe first reported case of TA in pregnancy in Hasan Sadikin Hospital with\nsuperimposed preeclampsia and pulmonary hypertension............................................
Background: This study aims to evaluate the effects of omission of the bladder\nflap formation at primary and repeat lower segment CS. Patients and\nMethods: The current study was randomized controlled trial conducted in\nWomen Health Hospital, Assiut University, Egypt between March 2017 and\nMay 2018 (ClinicalTrial.gov NCT03016273). Patients were divided into: Non\nbladder flap group: Uterine incision made 1 cm above the vesico-uterine reflection\nwithout incision and dissection of the bladder peritoneum and bladder\nflap group: Standard cesarean section technique with incision and dissection\nof a bladder flap prior to uterine incision. Results: The study included\n150 patients (75 in each arm). The most common indication for CS in both\ngroups was repeated CS. Non-bladder flap group, compared with flap group,\nshowed shorter skin-incision to delivery time and total operative time, and\nsignificantly lower mean estimated blood loss and postoperative pain score.\nNon-bladder flap group, compared with flap group, was more likely to\nshow postoperative microhematuria. The two groups required approximately\nthe same time for post-operative defecation. Conclusion: Omission\nof bladder flap formation during CS is associated with shorter operative\ntime, less blood loss, less postoperative pain and lower incidence of postoperative\nhematuria....
Background: Preterm labor is a serious cause of neonatal morbidity and\nmortality. This study aims to compare the effects of nifedipine, Magnesium\nsulfate and ritodrine as tocolytic drugs in patients presented with threatened\npreterm labor. Patients and Methods: The current study was randomized\ncontrolled trial conducted in Sohag Teaching Hospital between November\n2015 and September 2016. Patients were divided into: Group A: 101 patients\nreceived intravenous ritodrine infusion; Group B: 101 patients received\nintravenous magnesium sulfate; Group C: 101 patients received oral nifedipine.\nDifferent maternal and neonatal outcomes were assessed. Results: The\nbaseline criteria were homogenous among the study groups with no statistically\nsignificant differences. There is no difference between each other group\nregarding the need for additional tocolysis or the rate of recurrence of labour\npains. Nifedipine was associated with the least length of hospital stay. There is\nno difference between all groups regarding the rate of preterm delivery before\nfull steroid dose (p > 0.05). However, nifedipine group was the least one in the\nrate of occurrence of preterm delivery within 7 days from initiation of tocolytic\ntherapy. Similarly, nifedipine group was associated with higher gestational age\nat delivery and significant prolongation of pregnancy than the other groups.\nConclusion: Oral nifedipine use was associated with less recurrence of labor\npains, less need for additional tocolysis, less duration of hospital stay, and more\npatient satisfaction in patients with threatened preterm labour....
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